diff --git a/src/spikeinterface/sortingcomponents/motion/medicine.py b/src/spikeinterface/sortingcomponents/motion/medicine.py
new file mode 100644
index 0000000000..d8e4f1e9a5
--- /dev/null
+++ b/src/spikeinterface/sortingcomponents/motion/medicine.py
@@ -0,0 +1,102 @@
+import numpy as np
+
+from .motion_utils import Motion
+import tempfile
+import shutil
+from pathlib import Path
+
+from .motion_utils import get_spatial_windows
+
+
+class MedicineRegistration:
+    """ """
+
+    name = "medicine"
+    need_peak_location = True
+    params_doc = """
+
+    """
+
+    @classmethod
+    def run(
+        cls,
+        recording,
+        peaks,
+        peak_locations,
+        direction,
+        # unsed need to be adapted
+        rigid,
+        win_shape,
+        win_step_um,
+        win_scale_um,
+        win_margin_um,
+        verbose,
+        progress_bar,
+        extra,
+        bin_s=1.0,
+        ## medicine specific kwargs propagated to the lib
+        motion_bound=800,
+        time_kernel_width=30,
+        activity_network_hidden_features=(256, 256),
+        amplitude_threshold_quantile=0.0,
+        batch_size=4096,
+        training_steps=10_000,
+        initial_motion_noise=0.1,
+        motion_noise_steps=2000,
+        optimizer=None,
+        learning_rate=0.0005,
+        epsilon=1e-3,
+    ):
+
+        from medicine import run_medicine
+
+        # folder = Path(tempfile.gettempdir())
+
+        if rigid:
+            # force one bin
+            num_depth_bins = 1
+        else:
+
+            # we use the spatial window mechanism only to estimate the number one spatial bins
+            dim = ["x", "y", "z"].index(direction)
+            contact_depths = recording.get_channel_locations()[:, dim]
+
+            deph_range = max(contact_depths) - min(contact_depths)
+            if win_margin_um is not None:
+                deph_range = deph_range - 2 * win_margin_um
+            num_depth_bins = max(int(np.round(deph_range / win_scale_um)), 1)
+            print("num_depth_bins", num_depth_bins)
+
+        if optimizer is None:
+            import torch
+
+            optimizer = torch.optim.Adam
+
+        trainer, time_bins, depth_bins, pred_motion = run_medicine(
+            peak_amplitudes=peaks["amplitude"],
+            peak_depths=peak_locations[direction],
+            peak_times=peaks["sample_index"] / recording.get_sampling_frequency(),
+            time_bin_size=bin_s,
+            num_depth_bins=num_depth_bins,
+            output_dir=None,
+            plot_figures=False,
+            motion_bound=motion_bound,
+            time_kernel_width=time_kernel_width,
+            activity_network_hidden_features=activity_network_hidden_features,
+            amplitude_threshold_quantile=amplitude_threshold_quantile,
+            batch_size=batch_size,
+            training_steps=training_steps,
+            initial_motion_noise=initial_motion_noise,
+            motion_noise_steps=motion_noise_steps,
+            optimizer=optimizer,
+            learning_rate=learning_rate,
+            epsilon=epsilon,
+        )
+
+        motion = Motion(
+            displacement=[np.array(pred_motion)],
+            temporal_bins_s=[np.array(time_bins)],
+            spatial_bins_um=np.array(depth_bins),
+        )
+
+        return motion
diff --git a/src/spikeinterface/sortingcomponents/motion/motion_estimation.py b/src/spikeinterface/sortingcomponents/motion/motion_estimation.py
index 8a4daeb808..a285ad5064 100644
--- a/src/spikeinterface/sortingcomponents/motion/motion_estimation.py
+++ b/src/spikeinterface/sortingcomponents/motion/motion_estimation.py
@@ -11,6 +11,7 @@
 from .decentralized import DecentralizedRegistration
 from .iterative_template import IterativeTemplateRegistration
 from .dredge import DredgeLfpRegistration, DredgeApRegistration
+from .medicine import MedicineRegistration
 
 
 # estimate_motion > infer_motion
@@ -130,7 +131,13 @@ def estimate_motion(
         return motion
 
 
-_methods_list = [DecentralizedRegistration, IterativeTemplateRegistration, DredgeLfpRegistration, DredgeApRegistration]
+_methods_list = [
+    DecentralizedRegistration,
+    IterativeTemplateRegistration,
+    DredgeLfpRegistration,
+    DredgeApRegistration,
+    MedicineRegistration,
+]
 estimate_motion_methods = {m.name: m for m in _methods_list}
 method_doc = make_multi_method_doc(_methods_list)
 estimate_motion.__doc__ = estimate_motion.__doc__.format(method_doc=method_doc)