Can I use seq2HLA for cancer scRNA-seq data?

[levinhein]

Can I use seq2HLA for cancer scRNA-seq data?

[sebboegel]

Dear levinhein,

i havent tried this yet. In principle it works for any paired end fastq as input. However, the lower the expression (i.e. the lower the number of reads), the more insecure are the results. Maybe give it a try with pseudo-bulk as comparison. I would be very interested in the results.

Sebastian
[email protected]