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LongSom: detection of somatic variants in long-read scRNA-seq data.

LongSom is a tool for detecting somatic SNVs (including mitochondrial ones, "mtSNVS"), fusions, and CNAs in high-quality (PacBio, Nanopore R10.4) long-read scRNA-seq data from cancer biopsies, and subsequently reconstructing subclonal heterogeneity, based on those variants.

Wiki contents

How it works

Installation

Preparing input

Running LongSom

Understanding output