diff --git a/.github/workflows/CI.yaml b/.github/workflows/CI.yaml
index dd072768d..c27dfac9c 100644
--- a/.github/workflows/CI.yaml
+++ b/.github/workflows/CI.yaml
@@ -27,10 +27,7 @@ jobs:
       fail-fast: false
       matrix:
         python-version: [3.9, "3.10"]
-        openmm: ["8.0", "7.7"]
-        include:
-          - openmm: "dev"
-            python-version: "3.10"
+        openmm: ["dev"]
 
     env:
       OPENMM: ${{ matrix.openmm }}
@@ -52,14 +49,14 @@ jobs:
         with:
           environment-file: devtools/conda-envs/test_env.yaml
           environment-name: test
-          channels: jaimergp/label/unsupported-cudatoolkit-shim,conda-forge/label/openmm_dev,conda-forge,openeye
-          channel-priority: flexible
+          channels: jaimergp/label/unsupported-cudatoolkit-shim,conda-forge/label/openmm_rc,conda-forge,openeye
+          channel-priority: strict
           cache-env: true
           cache-downloads: true
           extra-specs: |
             python==${{ matrix.python-version }}
-            openmmtools==0.23.0
-            openmm==8.0.0dev3
+            openmmtools==0.23.1
+            openmm==8.1.0rc1
 
       - name: Setup micromamba
         if: ${{ matrix.openmm != 'dev' }}
diff --git a/.github/workflows/self-hosted-gpu-test.yml b/.github/workflows/self-hosted-gpu-test.yml
index a05cb6f96..0f97b1197 100644
--- a/.github/workflows/self-hosted-gpu-test.yml
+++ b/.github/workflows/self-hosted-gpu-test.yml
@@ -64,10 +64,11 @@ jobs:
       - uses: mamba-org/provision-with-micromamba@main
         with:
           environment-file: devtools/conda-envs/test_env.yaml
-          channels: conda-forge,openeye
+          channels: conda-forge/label/openmm_rc,conda-forge,openeye
+          channel-priority: strict
           extra-specs: |
             python==3.9
-            openmm>=8.0
+            openmm==8.1.0rc1
             cudatoolkit==11.7
             pymbar<4