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DESCRIPTION
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Package: hlabud
Title: Methods for Access and Analysis of the Human Leukocyte Antigen (HLA) Gene Sequence Alignments from IMGTHLA
Version: 2.0.0
Authors@R: c(
person("Kamil", "Slowikowski", email = "[email protected]", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-2843-6370"))
)
Description: Fetch sequence alignment data from the IMGTHLA database by Robinson et al (2020) <doi:10.1093/nar/gkz950>, automatically convert the sequence alignments into convenient R matrices ready for downstream analysis. The vignette shows examples of using the one-hot encoding of the data with logistic regression and dimensionality reduction. Data is downloaded lazily, as-needed, and cached in a user-configurable folder.
License: GPL (>= 3)
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
URL: https://github.com/slowkow/hlabud, https://slowkow.github.io/hlabud/
BugReports: https://github.com/slowkow/hlabud/issues
Depends:
R (>= 2.10)
LazyData: true
Imports:
curl,
dplyr,
glue,
jsonlite,
magrittr,
onehot,
rappdirs,
rlang,
stats,
stringr,
tibble,
tidyr
Suggests:
data.table,
ggplot2,
ggrepel,
ggstance,
knitr,
NGLVieweR,
parameters,
pbapply,
prettydoc,
readr,
rmarkdown,
scales,
testthat (>= 3.0.0),
uwot
Config/testthat/edition: 3