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Support polyG tail trimming
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@sfchen sfchen released this 05 Dec 06:46
· 351 commits to master since this release
v0.10.0
1f42298
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Learn about vigilant mode.

For Illumina NextSeq/NovaSeq data, polyG can happen in read tails since G means no signal in the Illumina two-color systems. fastp can detect the polyG in read tails and trim them. This feature is enabled for NextSeq/NovaSeq data by default, and you can specify -g or --trim_poly_g to enable it for any data, or specify -G or --disable_trim_poly_g to disable it. NextSeq/NovaSeq data is detected by the machine ID in the FASTQ records.

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