A Deep Learning Model to see which classifies Brain MRI on the basis of the dementia (AD). The images are classified as follows - Mildly Demented, Moderate Demented, Non Demented, Very Mild Demented.
The Brain MRI data for the project was taken from the Kaggle dataset <here>. It can be used to classify MRI into Mildly Demented, Moderate Demented, Non Demented, Very Mild Demented. Since
Alzheimer's(AD), according to the exact definition - is a type of dementia that effects memory, thinking and behavior. The general hypothesis regarding AD is that it prevents internal parts of cells from running well.
In the Brain MRI data, two abnormal structures are obtained - namely plaques and tangles which are the prime suspects in damaging and killing cells. The exact role of these structures is unknown, but there is a correlation between these structures and AD.
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Plaques are deposits of protein fragment called Beta-Amyloid that builds up in the spaces between nerve cells.
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Tangles are twisted fibres of protein called tau that builds up inside the cells.
People with AD tend to develop far more of these abnormal structures and in a predictable pattern - beginning in the areas important for memory and then spreading to other parts of the brain.
MRI Image courtesy of Sunnybrook and Women's College of Health Sciences Center.
The image here shows the difference between a normal brain(left) to one that has AD. As the disease progresses, the shrinkage of the brain continues - increasing the severity of the symptoms.
Our main aim is to classifies these abnormal structures and use the data to train a location specific model(either CNN or other) to pinpoint the location of the structures. If the model is robust, it can even be used to detect Early Onset AD. Our aim is just that - to correctly identify and classify the MRI data into the classes we defined above.
Note: This is my own Research prjoect and is suseptible to a lot of mistakes. It can become a "thing" if it leads to something substantial.
Alzhemist is something that has been on top of my mind for a long time. Neurodegenrative disorders, or in general the ability of lose control of your mind is one of my biggest fears. While I can't help cure it, I can do something that I am half good at and Alzemist is just that.