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4208414

amolin19 edited this page May 19, 2021 · 1 revision

4208414 - C-reactive protein measurement

C-reactive protein (CRP) is a substance produced by the liver in response to inflammation. A high level of CRP in the blood is a marker of inflammation. It can be caused by a wide variety of conditions, from infection to cancer. High CRP levels can also indicate that there’s inflammation in the arteries of the heart, which can mean a higher risk of heart attack. However, the CRP test is an extremely nonspecific test, and CRP levels can be elevated in any inflammatory condition. 1

8840

In the OMOP vocabulary 8840 is a Standard Concept that represents the unit milligram per deciliter (mg/dL)

Plausible Low Value

0.1

Plausible High Value

50.00

Rationale

Normal CRP test yields values <= 10 mg/L (or 1 mg/dL) 2. Lower levels, 0.3 to 1 mg/dL are possible 3, as are values as large as 50 mg/dL (associated with bacterial infections) 3. The literature, combined with a data-driven approach to empirically establish possible low and high values, leads us to choose 0.1 and 50.

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