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Fixes #2875 NTR-granzyme H-associated CD8 T cell #2895

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Fixes #2875 NTR-granzyme H-associated CD8 T cell #2895

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91f1519
Fixes #2875 NTR-granzyme H-associated CD8 T cell
Caroline-99 Jan 10, 2025
b1938f1
Update cl-edit.owl
Caroline-99 Jan 10, 2025
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14 changes: 14 additions & 0 deletions src/ontology/cl-edit.owl
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Original file line number Diff line number Diff line change
Expand Up @@ -3145,6 +3145,7 @@ Declaration(Class(obo:CL_4052028))
Declaration(Class(obo:CL_4052029))
Declaration(Class(obo:CL_4052030))
Declaration(Class(obo:CL_4052031))
Declaration(Class(obo:CL_4052032))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand Down Expand Up @@ -3206,6 +3207,7 @@ Declaration(Class(obo:PR_000002030))
Declaration(Class(obo:PR_000002123))
Declaration(Class(obo:PR_000003264))
Declaration(Class(obo:PR_000003472))
Declaration(Class(obo:PR_000003490))
Declaration(Class(obo:PR_000004691))
Declaration(Class(obo:PR_000004919))
Declaration(Class(obo:PR_000005444))
Expand Down Expand Up @@ -33490,6 +33492,18 @@ AnnotationAssertion(rdfs:label obo:CL_4052031 "respiratory airway secretory cell
SubClassOf(obo:CL_4052031 obo:CL_1100001)
SubClassOf(obo:CL_4052031 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002051))

# Class: obo:CL_4052032 (granzyme H-associated CD8 T cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") obo:IAO_0000115 obo:CL_4052032 "A CD8 T cell characterized by high expression of Granzyme H (GZMH). This cell exhibits a restricted TCR repertoire and elevated expression of cytotoxic, exhaustion, and type I interferon-stimulated gene signatures compared to controls.")
AnnotationAssertion(terms:contributor obo:CL_4052032 <https://orcid.org/0000-0002-3958-7465>)
AnnotationAssertion(terms:contributor obo:CL_4052032 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052032 "2025-01-10T10:14:31Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") oboInOwl:hasExactSynonym obo:CL_4052032 "granzyme H+ CD8 T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052032 "GZMH+ CD8+ T cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35389781") rdfs:comment obo:CL_4052032 "This cell type is significantly expanded in systemic lupus erythematosus (SLE) patients. Unlike other CD8 T cell populations, GZMH+ CD8 T cells can comprise up to 50% of all lymphocytes in some SLE patients.")
AnnotationAssertion(rdfs:label obo:CL_4052032 "granzyme H-associated CD8 T cell")
EquivalentClasses(obo:CL_4052032 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000003490)))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
Expand Down
3 changes: 2 additions & 1 deletion src/ontology/imports/pr_terms.txt
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Original file line number Diff line number Diff line change
Expand Up @@ -50,4 +50,5 @@ PR:000016626
PR:000003472
PR:000012318
PR:000064867
PR:000001440
PR:000001440
PR:000003490
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